p53-Dependent Senescence in Mesenchymal Stem Cells under Chronic Normoxia Is Potentiated by Low-Dose γ-Irradiation

Mesenchymal stem cells (MSCs) are a source of adult multipotent cells important in tissue regeneration. Murine MSCs are known to proliferate poorly in vitro under normoxia. The aim of this study is to analyze the interaction of nonphysiological high oxygen and low-dose γ-irradiation onto growth, sen...

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Detalles Bibliográficos
Autores principales: Höfig, Ines, Ingawale, Yashodhara, Atkinson, Michael J., Hertlein, Heidi, Nelson, Peter J., Rosemann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695678/
https://www.ncbi.nlm.nih.gov/pubmed/26788069
http://dx.doi.org/10.1155/2016/6429853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695678/
https://www.ncbi.nlm.nih.gov/pubmed/26788069
http://dx.doi.org/10.1155/2016/6429853

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