Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo

BACKGROUND: Currently, direct conversion from somatic cells to neurons requires virus-mediated delivery of at least one transcriptional factor or a combination of several small-molecule compounds. Delivery of transcriptional factors may affect genome stability, while small-molecule compounds may req...

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Detalles Bibliográficos
Autores principales: He, Songwei, Guo, Yiping, Zhang, Yixin, Li, Yuan, Feng, Chengqian, Li, Xiang, Lin, Lilong, Guo, Lin, Wang, Haitao, Liu, Chunhua, Zheng, Yi, Luo, Chuanming, Liu, Qiang, Wang, Fuhui, Sun, Hao, Liang, Lining, Li, Lingyu, Su, Huanxing, Chen, Jiekai, Pei, Duanqing, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696146/
https://www.ncbi.nlm.nih.gov/pubmed/26719791
http://dx.doi.org/10.1186/s13619-015-0027-6

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