Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation

BACKGROUND: Total body irradiation (TBI) has been part of standard conditioning regimens before allogeneic stem cell transplantation for many years. Its effect on normal tissue in these patients has not been studied extensively. METHOD: We studied the in vivo cytogenetic effects of TBI and high-dose...

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Detalles Bibliográficos
Autores principales: Massenkeil, G., Zschieschang, P., Thiel, G., Hemmati, P. G., Budach, V., Dörken, B., Pross, J., Arnold, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696175/
https://www.ncbi.nlm.nih.gov/pubmed/26715553
http://dx.doi.org/10.1186/s13014-015-0576-4

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