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Using host-pathogen protein interactions to identify and characterize Francisella tularensis virulence factors

BACKGROUND: Francisella tularensis is a select bio-threat agent and one of the most virulent intracellular pathogens known, requiring just a few organisms to establish an infection. Although several virulence factors are known, we lack an understanding of virulence factors that act through host-path...

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Detalles Bibliográficos
Autores principales: Wallqvist, Anders, Memišević, Vesna, Zavaljevski, Nela, Pieper, Rembert, Rajagopala, Seesandra V., Kwon, Keehwan, Yu, Chenggang, Hoover, Timothy A., Reifman, Jaques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696196/
https://www.ncbi.nlm.nih.gov/pubmed/26714771
http://dx.doi.org/10.1186/s12864-015-2351-1