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Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line
BACKGROUND: Next-generation sequencing (NGS) technologies have changed our understanding of the variability of the human genome. However, the identification of genome structural variations based on NGS approaches with read lengths of 35–300 bases remains a challenge. Single-molecule optical mapping...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696294/ https://www.ncbi.nlm.nih.gov/pubmed/26719794 http://dx.doi.org/10.1186/s13742-015-0106-1 |