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Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement

BACKGROUND: Complement promotes neuroinflammation and injury in models of stroke. However, complement is also being increasingly implicated in repair and regeneration after central nervous system (CNS) injury, and some complement deficiencies have been shown to provide acute, but not subacute, prote...

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Detalles Bibliográficos
Autores principales: Alawieh, Ali, Elvington, Andrew, Zhu, Hong, Yu, Jin, Kindy, Mark S., Atkinson, Carl, Tomlinson, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696299/
https://www.ncbi.nlm.nih.gov/pubmed/26714866
http://dx.doi.org/10.1186/s12974-015-0464-8