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Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement
BACKGROUND: Complement promotes neuroinflammation and injury in models of stroke. However, complement is also being increasingly implicated in repair and regeneration after central nervous system (CNS) injury, and some complement deficiencies have been shown to provide acute, but not subacute, prote...
Autores principales: | Alawieh, Ali, Elvington, Andrew, Zhu, Hong, Yu, Jin, Kindy, Mark S., Atkinson, Carl, Tomlinson, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696299/ https://www.ncbi.nlm.nih.gov/pubmed/26714866 http://dx.doi.org/10.1186/s12974-015-0464-8 |
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