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Modified mRNA as an alternative to plasmid DNA (pDNA) for transcript replacement and vaccination therapy
Introduction: Current gene therapy involves replacement of defective gene by delivery of healthy genetic material to precede normal function. Virus-mediated gene delivery is the most successful and efficient method for gene therapy, but it has been challenged due to serious safety concerns. Converse...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Informa Healthcare
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696419/ https://www.ncbi.nlm.nih.gov/pubmed/26125492 http://dx.doi.org/10.1517/14712598.2015.1057563 |