Cargando…
Drosophila Rabex-5 restricts Notch activity in hematopoietic cells and maintains hematopoietic homeostasis
Hematopoietic homeostasis requires the maintenance of a reservoir of undifferentiated blood cell progenitors and the ability to replace or expand differentiated blood cell lineages when necessary. Multiple signaling pathways function in these processes, but how their spatiotemporal control is establ...
Autores principales: | Reimels, Theresa A., Pfleger, Cathie M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696494/ https://www.ncbi.nlm.nih.gov/pubmed/26567216 http://dx.doi.org/10.1242/jcs.174433 |
Ejemplares similares
-
Rab5 and Rab11 maintain hematopoietic homeostasis by restricting multiple signaling pathways in Drosophila
por: Yu, Shichao, et al.
Publicado: (2021) -
A conserved, N-terminal tyrosine signal directs Ras for inhibition by Rabex-5
por: Washington, Chalita, et al.
Publicado: (2020) -
Molecular mechanism for Rabex-5 GEF activation by Rabaptin-5
por: Zhang, Zhe, et al.
Publicado: (2014) -
Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster()
por: Thomas, Chloe, et al.
Publicado: (2014) -
Expression of RABEX-5 and its clinical significance in prostate cancer
por: Zhang, Hongtuan, et al.
Publicado: (2014)