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CDK9 and its repressor LARP7 modulate cardiomyocyte proliferation and response to injury in the zebrafish heart
Cyclin dependent kinase (Cdk)9 acts through the positive transcription elongation factor-b (P-TEFb) complex to activate and expand transcription through RNA polymerase II. It has also been shown to regulate cardiomyocyte hypertrophy, with recent evidence linking it to cardiomyocyte proliferation. We...
Autores principales: | Matrone, Gianfranco, Wilson, Kathryn S., Maqsood, Sana, Mullins, John J., Tucker, Carl S., Denvir, Martin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696495/ https://www.ncbi.nlm.nih.gov/pubmed/26542022 http://dx.doi.org/10.1242/jcs.175018 |
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