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Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca(2+) in Hansenula polymorpha
Processes taking place in the secretory organelles require Ca(2+) and Mn(2+), which in yeast are supplied by the Pmr1 ion pump. Here we observed that in the yeast Hansenula polymorpha Ca(2+) deficiency in the secretory pathway caused by Pmr1 inactivation is exacerbated by (i) the ret1-27 mutation af...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696657/ https://www.ncbi.nlm.nih.gov/pubmed/26717478 http://dx.doi.org/10.1371/journal.pone.0145915 |