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Expression of Nitric Oxide-Transporting Aquaporin-1 Is Controlled by KLF2 and Marks Non-Activated Endothelium In Vivo

The flow-responsive transcription factor Krüppel-like factor 2 (KLF2) maintains an anti-coagulant, anti-inflammatory endothelium with sufficient nitric oxide (NO)-bioavailability. In this study, we aimed to explore, both in vitro and in human vascular tissue, expression of the NO-transporting transm...

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Detalles Bibliográficos
Autores principales: Fontijn, Ruud D., Volger, Oscar L., van der Pouw-Kraan, Tineke C., Doddaballapur, Anuradha, Leyen, Thomas, Baggen, Josefien M., Boon, Reinier A., Horrevoets, Anton J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696733/
https://www.ncbi.nlm.nih.gov/pubmed/26717516
http://dx.doi.org/10.1371/journal.pone.0145777