ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell. In breast cancer, ELF5 is a key transcriptional determinant of tumor subtype and has been implicated in the development of...

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Detalles Bibliográficos
Autores principales: Gallego-Ortega, David, Ledger, Anita, Roden, Daniel L., Law, Andrew M. K., Magenau, Astrid, Kikhtyak, Zoya, Cho, Christina, Allerdice, Stephanie L., Lee, Heather J., Valdes-Mora, Fatima, Herrmann, David, Salomon, Robert, Young, Adelaide I. J., Lee, Brian Y., Sergio, C. Marcelo, Kaplan, Warren, Piggin, Catherine, Conway, James R. W., Rabinovich, Brian, Millar, Ewan K. A., Oakes, Samantha R., Chtanova, Tatyana, Swarbrick, Alexander, Naylor, Matthew J., O’Toole, Sandra, Green, Andrew R., Timpson, Paul, Gee, Julia M. W., Ellis, Ian O., Clark, Susan J., Ormandy, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696735/
https://www.ncbi.nlm.nih.gov/pubmed/26717410
http://dx.doi.org/10.1371/journal.pbio.1002330

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