Cargando…

Cellular Responses and Tissue Depots for Nanoformulated Antiretroviral Therapy

Long-acting nanoformulated antiretroviral therapy (nanoART) induces a range of innate immune migratory, phagocytic and secretory cell functions that perpetuate drug depots. While recycling endosomes serve as the macrophage subcellular depots, little is known of the dynamics of nanoART-cell interacti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martinez-Skinner, Andrea L., Araínga, Mariluz A., Puligujja, Pavan, Palandri, Diana L., Baldridge, Hannah M., Edagwa, Benson J., McMillan, JoEllyn M., Mosley, R. Lee, Gendelman, Howard E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696780/ https://www.ncbi.nlm.nih.gov/pubmed/26716700 http://dx.doi.org/10.1371/journal.pone.0145966

Ejemplares similares

Creation of a Long-Acting Nanoformulated 2′,3′-Dideoxy-3′-Thiacytidine
por: Guo, Dongwei, et al.
Publicado: (2017)

Optimizing the preparation and stability of decorated antiretroviral drug nanocrystals
por: Zhou, Tian, et al.
Publicado: (2018)

Opposing regulation of endolysosomal pathways by long-acting nanoformulated antiretroviral therapy and HIV-1 in human macrophages
por: Araínga, Mariluz, et al.
Publicado: (2015)

Nanoformulated Antiretroviral Therapy Attenuates Brain Metabolic Oxidative Stress
por: Montenegro-Burke, J. Rafael, et al.
Publicado: (2018)

ProTide generated long-acting abacavir nanoformulations
por: Lin, Zhiyi, et al.
Publicado: (2018)

Methods Development for Blood Borne Macrophage Carriage of Nanoformulated Antiretroviral Drugs
por: Balkundi, Shantanu, et al.
Publicado: (2010)

Magnetic resonance imaging of folic acid-coated magnetite nanoparticles reflects tissue biodistribution of long-acting antiretroviral therapy
por: Li, Tianyuzi, et al.
Publicado: (2015)

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes
por: Edagwa, Benson J., et al.
Publicado: (2014)

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles
por: Zhou, Tian, et al.
Publicado: (2017)

Comparative manufacture and cell-based delivery of antiretroviral nanoformulations
por: Balkundi, Shantanu, et al.
Publicado: (2011)

Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques
por: McMillan, JoEllyn, et al.
Publicado: (2017)

A mature macrophage is a principal HIV-1 cellular reservoir in humanized mice after treatment with long acting antiretroviral therapy
por: Araínga, Mariluz, et al.
Publicado: (2017)

Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation
por: Ibrahim, Ibrahim M, et al.
Publicado: (2019)

Creation of a long-acting nanoformulated dolutegravir
por: Sillman, Brady, et al.
Publicado: (2018)

Dolutegravir Inhibition of Matrix Metalloproteinases Affects Mouse Neurodevelopment
por: Bade, Aditya N., et al.
Publicado: (2021)

Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution
por: Kevadiya, Bhavesh D., et al.
Publicado: (2018)

A Year-Long Extended Release Nanoformulated Cabotegravir Prodrug
por: Kulkarni, Tanmay A., et al.
Publicado: (2020)

Development of mannose-anchored thiolated amphotericin B nanocarriers for treatment of visceral leishmaniasis
por: Shahnaz, Gul, et al.
Publicado: (2017)

Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells
por: Kanmogne, Georgette D, et al.
Publicado: (2012)

Rod-shape theranostic nanoparticles facilitate antiretroviral drug biodistribution and activity in human immunodeficiency virus susceptible cells and tissues
por: Kevadiya, Bhavesh D., et al.
Publicado: (2020)

Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles
por: Cobb, Denise A., et al.
Publicado: (2021)

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
por: Boska, Michael, et al.
Publicado: (2010)

EcoHIV infection of mice establishes latent viral reservoirs in T cells and active viral reservoirs in macrophages that are sufficient for induction of neurocognitive impairment
por: Gu, Chao-Jiang, et al.
Publicado: (2018)

Europium sulfide nanoprobes predict antiretroviral drug delivery into HIV-1 cell and tissue reservoirs
por: Herskovitz, Jonathan, et al.
Publicado: (2021)

Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir
por: Gautam, Nagsen, et al.
Publicado: (2021)

CRISPR-Cas9 Mediated Exonic Disruption for HIV-1 Elimination
por: Herskovitz, Jonathan, et al.
Publicado: (2021)

HIV-1 cellular and tissue replication patterns in infected humanized mice
por: Araínga, Mariluz, et al.
Publicado: (2016)

An ultralong-acting tenofovir ProTide nanoformulation achieves monthslong HBV suppression
por: Das, Srijanee, et al.
Publicado: (2022)

A Link Between Methylglyoxal and Heart Failure During HIV-1 Infection
por: Dash, Prasanta K., et al.
Publicado: (2021)

Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice
por: McMillan, JoEllyn M., et al.
Publicado: (2018)

Pharmacotherapeutics of SARS-CoV-2 Infections
por: Kevadiya, Bhavesh D., et al.
Publicado: (2021)

Prodrug Therapies for Infectious and Neurodegenerative Diseases
por: Markovic, Milica, et al.
Publicado: (2022)

Application of Cryopreserved Human Hepatocytes in Trichloroethylene Risk Assessment: Relative Disposition of Chloral Hydrate to Trichloroacetate and Trichloroethanol
por: Bronley-DeLancey, Apryl, et al.
Publicado: (2006)

Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation
por: Deodhar, Suyash, et al.
Publicado: (2022)

Imaging and microarray analyses of cell cycle arrest and apoptosis by Human T cell Leukemia Virus type 1 (HTLV-1) Tax
por: Arainga-Ramirez, Mariluz, et al.
Publicado: (2011)

Identification of bovine leukemia virus tax function associated with host cell transcription, signaling, stress response and immune response pathway by microarray-based gene expression analysis
por: Arainga, Mariluz, et al.
Publicado: (2012)

Visualizing spatiotemporal dynamics of apoptosis after G1 arrest by human T cell leukemia virus type 1 Tax and insights into gene expression changes using microarray-based gene expression analysis
por: Arainga, Mariluz, et al.
Publicado: (2012)

Regulation of host cellular gene transcription by Bovine Leukemia Virus (BLV) Tax, wild type and mutants
por: Arainga-Ramirez, Mariluz, et al.
Publicado: (2011)

Ultra-long-acting (XLA) antivirals for chronic viral hepatitis
por: Soriano, Vicente, et al.
Publicado: (2022)

Adeno-Associated Viral Transfer of Glyoxalase-1 Blunts Carbonyl and Oxidative Stresses in Hearts of Type 1 Diabetic Rats
por: Alomar, Fadhel A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g25m1mjvski9je2ompaem5o0n2