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On the Recombination Rate Estimation in the Presence of Population Substructure
As recombination events are not uniformly distributed along the human genome, the estimation of fine-scale recombination maps, e.g. HapMap Project, has been one of the major research endeavors over the last couple of years. For simulation studies, these estimates provide realistic reference scenario...
Autores principales: | Hecker, Julian, Prokopenko, Dmitry, Lange, Christoph, Fier, Heide Löhlein |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696844/ https://www.ncbi.nlm.nih.gov/pubmed/26716445 http://dx.doi.org/10.1371/journal.pone.0145152 |
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