TM-25659-Induced Activation of FGF21 Level Decreases Insulin Resistance and Inflammation in Skeletal Muscle via GCN2 Pathways

The TAZ activator 2-butyl-5-methyl-6-(pyridine-3-yl)-3-[2′-(1H-tetrazole-5-yl)-biphenyl-4-ylmethyl]-3H-imidazo[4,5-b]pyridine] (TM-25659) inhibits adipocyte differentiation by interacting with peroxisome proliferator-activated receptor gamma. TM-25659 was previously shown to decrease weight gain in...

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Detalles Bibliográficos
Autores principales: Jung, Jong Gab, Yi, Sang-A, Choi, Sung-E, Kang, Yup, Kim, Tae Ho, Jeon, Ja Young, Bae, Myung Ae, Ahn, Jin Hee, Jeong, Hana, Hwang, Eun Sook, Lee, Kwan-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696994/
https://www.ncbi.nlm.nih.gov/pubmed/26537193
http://dx.doi.org/10.14348/molcells.2015.0100

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