Ear lobe crease: a marker of coronary artery disease?

The ear lobe crease (ELC) has been defined as a deep wrinkle that extends backwards from the tragus to the auricle. It has been proposed that ELC is a predictor of coronary artery disease (CAD). In this review, we consider the possible association between ELC and CAD. Our aim is to systematically ad...

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Autores principales: Agouridis, Aris P., Elisaf, Moses S., Nair, Devaki R., Mikhailidis, Dimitri P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
State of the Art Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697048/
https://www.ncbi.nlm.nih.gov/pubmed/26788075
http://dx.doi.org/10.5114/aoms.2015.56340
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author Agouridis, Aris P.
Elisaf, Moses S.
Nair, Devaki R.
Mikhailidis, Dimitri P.
author_facet Agouridis, Aris P.
Elisaf, Moses S.
Nair, Devaki R.
Mikhailidis, Dimitri P.
author_sort Agouridis, Aris P.
collection PubMed
description The ear lobe crease (ELC) has been defined as a deep wrinkle that extends backwards from the tragus to the auricle. It has been proposed that ELC is a predictor of coronary artery disease (CAD). In this review, we consider the possible association between ELC and CAD. Our aim is to systematically address all the relevant evidence in this field. There are many studies that support an association between ELC and CAD. However, other studies did not find such an association. A recent meta-analysis supports the hypothesis that ELC could be a marker of CAD. However, several limitations raise doubts as to whether we should accept this link.
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spelling pubmed-46970482016-01-19 Ear lobe crease: a marker of coronary artery disease? Agouridis, Aris P. Elisaf, Moses S. Nair, Devaki R. Mikhailidis, Dimitri P. Arch Med Sci State of the Art Paper The ear lobe crease (ELC) has been defined as a deep wrinkle that extends backwards from the tragus to the auricle. It has been proposed that ELC is a predictor of coronary artery disease (CAD). In this review, we consider the possible association between ELC and CAD. Our aim is to systematically address all the relevant evidence in this field. There are many studies that support an association between ELC and CAD. However, other studies did not find such an association. A recent meta-analysis supports the hypothesis that ELC could be a marker of CAD. However, several limitations raise doubts as to whether we should accept this link. Termedia Publishing House 2015-12-11 2015-12-10 /pmc/articles/PMC4697048/ /pubmed/26788075 http://dx.doi.org/10.5114/aoms.2015.56340 Text en Copyright © 2015 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle State of the Art Paper
Agouridis, Aris P.
Elisaf, Moses S.
Nair, Devaki R.
Mikhailidis, Dimitri P.
Ear lobe crease: a marker of coronary artery disease?
title Ear lobe crease: a marker of coronary artery disease?
title_full Ear lobe crease: a marker of coronary artery disease?
title_fullStr Ear lobe crease: a marker of coronary artery disease?
title_full_unstemmed Ear lobe crease: a marker of coronary artery disease?
title_short Ear lobe crease: a marker of coronary artery disease?
title_sort ear lobe crease: a marker of coronary artery disease?
topic State of the Art Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697048/
https://www.ncbi.nlm.nih.gov/pubmed/26788075
http://dx.doi.org/10.5114/aoms.2015.56340
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