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Inhibitory effects of metformin at low concentration on epithelial–mesenchymal transition of CD44(+)CD117(+) ovarian cancer stem cells

BACKGROUND: Although metformin, a first-line drug for treating diabetes, may play an important role in inhibition of epithelial ovarian cancer cell growth and cancer stem cells (CSCs), metformin at low dose showed less effect on the proliferation of ovarian cancer cells. In this study, we evaluated...

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Detalles Bibliográficos
Autores principales:	Zhang, Rongrong, Zhang, Ping, Wang, Hong, Hou, Dongming, Li, Wentao, Xiao, Guishan, Li, Chenwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697317/ https://www.ncbi.nlm.nih.gov/pubmed/26718286 http://dx.doi.org/10.1186/s13287-015-0249-0

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