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Dual Requirement of Cytokine and Activation Receptor Triggering for Cytotoxic Control of Murine Cytomegalovirus by NK Cells

Natural killer (NK) cells play a critical role in controlling murine cytomegalovirus (MCMV) and can mediate both cytokine production and direct cytotoxicity. The NK cell activation receptor, Ly49H, is responsible for genetic resistance to MCMV in C57BL/6 mice. Recognition of the viral m157 protein b...

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Detalles Bibliográficos
Autores principales:	Parikh, Bijal A., Piersma, Sytse J., Pak-Wittel, Melissa A., Yang, Liping, Schreiber, Robert D., Yokoyama, Wayne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697817/ https://www.ncbi.nlm.nih.gov/pubmed/26720279 http://dx.doi.org/10.1371/journal.ppat.1005323

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