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Activin Receptor-Like Kinase Receptors ALK5 and ALK1 Are Both Required for TGFβ-Induced Chondrogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells

INTRODUCTION: Bone marrow-derived mesenchymal stem cells (BMSCs) are promising for cartilage regeneration because BMSCs can differentiate into cartilage tissue-producing chondrocytes. Transforming Growth Factor β (TGFβ) is crucial for inducing chondrogenic differentiation of BMSCs and is known to si...

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Detalles Bibliográficos
Autores principales:	de Kroon, Laurie M. G., Narcisi, Roberto, Blaney Davidson, Esmeralda N., Cleary, Mairéad A., van Beuningen, Henk M., Koevoet, Wendy J. L. M., van Osch, Gerjo J. V. M., van der Kraan, Peter M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697836/ https://www.ncbi.nlm.nih.gov/pubmed/26720610 http://dx.doi.org/10.1371/journal.pone.0146124

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