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Tregs Modulate Lymphocyte Proliferation, Activation, and Resident-Memory T-Cell Accumulation within the Brain during MCMV Infection
Accumulation and retention of regulatory T-cells (Tregs) has been reported within post viral-encephalitic brains, however, the full extent to which these cells modulate neuroinflammation is yet to be elucidated. Here, we used Foxp3-DTR (diphtheria toxin receptor) knock-in transgenic mice, which upon...
Autores principales: | Prasad, Sujata, Hu, Shuxian, Sheng, Wen S., Singh, Amar, Lokensgard, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697843/ https://www.ncbi.nlm.nih.gov/pubmed/26720146 http://dx.doi.org/10.1371/journal.pone.0145457 |
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