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Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases
INTRODUCTION: Hypothyroidism is the most common endocrine disorder in children and presented with various sign and symptoms; its diagnosis needs a high index of suspicion. CASE PRESENTATION: We report 3 cases with unusual presentations of hypothyroidism and with delay in diagnosis that referred to P...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698140/ https://www.ncbi.nlm.nih.gov/pubmed/26734478 http://dx.doi.org/10.5812/ircmj.20306 |
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author | Ghaemi, Nosrat Bagheri, Sepideh Elmi, Saghi Mohammadzade Rezaee, Saber Elmi, Sam Erfani Sayyar, Reza |
author_facet | Ghaemi, Nosrat Bagheri, Sepideh Elmi, Saghi Mohammadzade Rezaee, Saber Elmi, Sam Erfani Sayyar, Reza |
author_sort | Ghaemi, Nosrat |
collection | PubMed |
description | INTRODUCTION: Hypothyroidism is the most common endocrine disorder in children and presented with various sign and symptoms; its diagnosis needs a high index of suspicion. CASE PRESENTATION: We report 3 cases with unusual presentations of hypothyroidism and with delay in diagnosis that referred to Pediatric Endocrine Outpatient Clinic in Mashhad University of Medical Sciences, Mashhad, Iran with different clinical manifestations. They had decreased Thyroxin (T4) and increased thyroid stimulating hormone (TSH) levels. One case had mental retardation and deafness, but the other two cases had normal neurodevelopment. Some additional interesting findings were as follows: short stature, delayed bone age, teeth eruption impairment, hair loss, anemia and hypercholesterolemia, persistent and long-term constipation that had led to several abdominal surgeries. After a year of hormonal replacement therapy, their growth parameters and hematological values improved. CONCLUSIONS: We recommend thyroid hormonal evaluation for any children with short stature, especially with delayed bone age, in order to detect and treat hypothyroidism at the right time. It seems that more attention to pediatric growth is necessary. |
format | Online Article Text |
id | pubmed-4698140 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Kowsar |
record_format | MEDLINE/PubMed |
spelling | pubmed-46981402016-01-05 Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases Ghaemi, Nosrat Bagheri, Sepideh Elmi, Saghi Mohammadzade Rezaee, Saber Elmi, Sam Erfani Sayyar, Reza Iran Red Crescent Med J Case Report INTRODUCTION: Hypothyroidism is the most common endocrine disorder in children and presented with various sign and symptoms; its diagnosis needs a high index of suspicion. CASE PRESENTATION: We report 3 cases with unusual presentations of hypothyroidism and with delay in diagnosis that referred to Pediatric Endocrine Outpatient Clinic in Mashhad University of Medical Sciences, Mashhad, Iran with different clinical manifestations. They had decreased Thyroxin (T4) and increased thyroid stimulating hormone (TSH) levels. One case had mental retardation and deafness, but the other two cases had normal neurodevelopment. Some additional interesting findings were as follows: short stature, delayed bone age, teeth eruption impairment, hair loss, anemia and hypercholesterolemia, persistent and long-term constipation that had led to several abdominal surgeries. After a year of hormonal replacement therapy, their growth parameters and hematological values improved. CONCLUSIONS: We recommend thyroid hormonal evaluation for any children with short stature, especially with delayed bone age, in order to detect and treat hypothyroidism at the right time. It seems that more attention to pediatric growth is necessary. Kowsar 2015-11-01 /pmc/articles/PMC4698140/ /pubmed/26734478 http://dx.doi.org/10.5812/ircmj.20306 Text en Copyright © 2015, Iranian Red Crescent Medical Journal. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Case Report Ghaemi, Nosrat Bagheri, Sepideh Elmi, Saghi Mohammadzade Rezaee, Saber Elmi, Sam Erfani Sayyar, Reza Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases |
title | Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases |
title_full | Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases |
title_fullStr | Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases |
title_full_unstemmed | Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases |
title_short | Delayed Diagnosis of Hypothyroidism in Children: Report of 3 Cases |
title_sort | delayed diagnosis of hypothyroidism in children: report of 3 cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698140/ https://www.ncbi.nlm.nih.gov/pubmed/26734478 http://dx.doi.org/10.5812/ircmj.20306 |
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