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Insights into open/closed conformations of the catalytically active human guanylate kinase as investigated by small-angle X-ray scattering
ABSTRACT: Bio-catalysis is the outcome of a subtle interplay between internal motions in enzymes and chemical kinetics. Small-angle X-ray scattering (SAXS) investigation of an enzyme’s internal motions during catalysis offers an integral view of the protein’s structural plasticity, dynamics, and fun...
Autores principales: | Jain, Rohit, Khan, Nazimuddin, Menzel, Andreas, Rajkovic, Ivan, Konrad, Manfred, Techert, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698301/ https://www.ncbi.nlm.nih.gov/pubmed/26446352 http://dx.doi.org/10.1007/s00249-015-1079-9 |
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