NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

Glutathione is the major intracellular redox buffer in the liver and is critical for hepatic detoxification of xenobiotics and other environmental toxins. Hepatic glutathione is also a major systemic store for other organs and thus impacts on pathologies such as Alzheimer's disease, Sickle Cell...

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Detalles Bibliográficos
Autores principales: Murray, Thomas V.A., Dong, Xuebin, Sawyer, Greta J., Caldwell, Anna, Halket, John, Sherwood, Roy, Quaglia, Alberto, Dew, Tracy, Anilkumar, Narayana, Burr, Simon, Mistry, Rajesh K., Martin, Daniel, Schröder, Katrin, Brandes, Ralf P., Hughes, Robin D., Shah, Ajay M., Brewer, Alison C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698376/
https://www.ncbi.nlm.nih.gov/pubmed/26472193
http://dx.doi.org/10.1016/j.freeradbiomed.2015.09.015

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