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Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
BACKGROUND: Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-tim...
Autores principales: | Pankhurst, Louise J, del Ojo Elias, Carlos, Votintseva, Antonina A, Walker, Timothy M, Cole, Kevin, Davies, Jim, Fermont, Jilles M, Gascoyne-Binzi, Deborah M, Kohl, Thomas A, Kong, Clare, Lemaitre, Nadine, Niemann, Stefan, Paul, John, Rogers, Thomas R, Roycroft, Emma, Smith, E Grace, Supply, Philip, Tang, Patrick, Wilcox, Mark H, Wordsworth, Sarah, Wyllie, David, Xu, Li, Crook, Derrick W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698465/ https://www.ncbi.nlm.nih.gov/pubmed/26669893 http://dx.doi.org/10.1016/S2213-2600(15)00466-X |
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