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Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study

BACKGROUND: Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome sequencing (WGS) could potentially provide a rapid and comprehensive diagnostic solution. In this prospective study, we compare real-tim...

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Detalles Bibliográficos
Autores principales: Pankhurst, Louise J, del Ojo Elias, Carlos, Votintseva, Antonina A, Walker, Timothy M, Cole, Kevin, Davies, Jim, Fermont, Jilles M, Gascoyne-Binzi, Deborah M, Kohl, Thomas A, Kong, Clare, Lemaitre, Nadine, Niemann, Stefan, Paul, John, Rogers, Thomas R, Roycroft, Emma, Smith, E Grace, Supply, Philip, Tang, Patrick, Wilcox, Mark H, Wordsworth, Sarah, Wyllie, David, Xu, Li, Crook, Derrick W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698465/
https://www.ncbi.nlm.nih.gov/pubmed/26669893
http://dx.doi.org/10.1016/S2213-2600(15)00466-X

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