Snord116 is critical in the regulation of food intake and body weight

Prader-Willi syndrome (PWS) is the predominant genetic cause of obesity in humans. Recent clinical reports have suggested that micro-deletion of the Snord116 gene cluster can lead to PWS, however, the extent of the contributions of the encoded snoRNAs is unknown. Here we show that mice lacking Snord...

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Detalles Bibliográficos
Autores principales: Qi, Yue, Purtell, Louise, Fu, Melissa, Lee, Nicola J., Aepler, Julia, Zhang, Lei, Loh, Kim, Enriquez, Ronaldo F., Baldock, Paul A., Zolotukhin, Sergei, Campbell, Lesley V., Herzog, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698587/
https://www.ncbi.nlm.nih.gov/pubmed/26726071
http://dx.doi.org/10.1038/srep18614

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