Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus

The development of the synovial membrane was analyzed in serial sections of 21 temporomandibular joints of human fetuses at 9 to 13 weeks of gestation. Sections of two fetuses at 12 weeks of development were used to perform immunohistochemical expression of the markers CD68 and Hsp27 on the synovial...

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Detalles Bibliográficos
Autores principales: de Moraes, L.O. Carvalho, Tedesco, R.C., Arraéz-Aybar, L.A., Klein, O., Mérida-Velasco, J.R., Alonso, L.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698616/
https://www.ncbi.nlm.nih.gov/pubmed/26708184
http://dx.doi.org/10.4081/ejh.2015.2569
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author de Moraes, L.O. Carvalho
Tedesco, R.C.
Arraéz-Aybar, L.A.
Klein, O.
Mérida-Velasco, J.R.
Alonso, L.G.
author_facet de Moraes, L.O. Carvalho
Tedesco, R.C.
Arraéz-Aybar, L.A.
Klein, O.
Mérida-Velasco, J.R.
Alonso, L.G.
author_sort de Moraes, L.O. Carvalho
collection PubMed
description The development of the synovial membrane was analyzed in serial sections of 21 temporomandibular joints of human fetuses at 9 to 13 weeks of gestation. Sections of two fetuses at 12 weeks of development were used to perform immunohistochemical expression of the markers CD68 and Hsp27 on the synovial lining. Macrophage-like type A and fibroblast-like type B cells, which express CD68 and Hsp27, respectively, were observed at the twelfth week of development. Our results suggest that the development of the synovial membrane is related to the vascularization of the joint and the formation of the articular cavities.
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spelling pubmed-46986162016-01-15 Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus de Moraes, L.O. Carvalho Tedesco, R.C. Arraéz-Aybar, L.A. Klein, O. Mérida-Velasco, J.R. Alonso, L.G. Eur J Histochem Original Paper The development of the synovial membrane was analyzed in serial sections of 21 temporomandibular joints of human fetuses at 9 to 13 weeks of gestation. Sections of two fetuses at 12 weeks of development were used to perform immunohistochemical expression of the markers CD68 and Hsp27 on the synovial lining. Macrophage-like type A and fibroblast-like type B cells, which express CD68 and Hsp27, respectively, were observed at the twelfth week of development. Our results suggest that the development of the synovial membrane is related to the vascularization of the joint and the formation of the articular cavities. PAGEPress Publications, Pavia, Italy 2015-11-26 /pmc/articles/PMC4698616/ /pubmed/26708184 http://dx.doi.org/10.4081/ejh.2015.2569 Text en ©Copyright L.O. Carvalho de Moraes et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
de Moraes, L.O. Carvalho
Tedesco, R.C.
Arraéz-Aybar, L.A.
Klein, O.
Mérida-Velasco, J.R.
Alonso, L.G.
Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus
title Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus
title_full Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus
title_fullStr Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus
title_full_unstemmed Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus
title_short Development of Synovial Membrane in the Temporomandibular Joint of the Human Fetus
title_sort development of synovial membrane in the temporomandibular joint of the human fetus
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698616/
https://www.ncbi.nlm.nih.gov/pubmed/26708184
http://dx.doi.org/10.4081/ejh.2015.2569
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