Genetic studies of plasma analytes identify novel potential biomarkers for several complex traits

Genome-wide association studies of 146 plasma protein levels in 818 individuals revealed 56 genome-wide significant associations (28 novel) with 47 analytes. Loci associated with plasma levels of 39 proteins tested have been previously associated with various complex traits such as heart disease, in...

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Detalles Bibliográficos
Autores principales: Deming, Yuetiva, Xia, Jian, Cai, Yefei, Lord, Jenny, Del-Aguila, Jorge L., Fernandez, Maria Victoria, Carrell, David, Black, Kathleen, Budde, John, Ma, ShengMei, Saef, Benjamin, Howells, Bill, Bertelsen, Sarah, Bailey, Matthew, Ridge, Perry G., Holtzman, David, Morris, John C., Bales, Kelly, Pickering, Eve H., Lee, Jin-Moo, Heitsch, Laura, Kauwe, John, Goate, Alison, Piccio, Laura, Cruchaga, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698720/
https://www.ncbi.nlm.nih.gov/pubmed/36647296
http://dx.doi.org/10.1038/srep18092

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