Cargando…
Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in Mice
BACKGROUND & AIMS: Perturbations in pancreatic ductal bicarbonate secretion cause chronic pancreatitis. The physiologic mechanism of ductal secretion is known, but its transcriptional control is not. We determine the role of the transcription factor hematopoietically expressed homeobox protein (...
Autores principales: | Ferreira, Mark J., McKenna, Lindsay B., Zhang, Jia, Reichert, Maximilian, Bakir, Basil, Buza, Elizabeth L., Furth, Emma E., Bogue, Clifford W., Rustgi, Anil K., Kaestner, Klaus H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698881/ https://www.ncbi.nlm.nih.gov/pubmed/26740970 http://dx.doi.org/10.1016/j.jcmgh.2015.06.007 |
Ejemplares similares
-
The diabetes gene Hhex maintains δ-cell differentiation and islet function
por: Zhang, Jia, et al.
Publicado: (2014) -
Hhex Is Necessary for the Hepatic Differentiation of Mouse ES Cells and Acts via Vegf Signaling
por: Arterbery, Adam S., et al.
Publicado: (2016) -
Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer
por: Moreira, Leticia, et al.
Publicado: (2017) -
Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization
por: Takano, Shigetsugu, et al.
Publicado: (2016) -
Acute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2a
por: Shields, Benjamin J., et al.
Publicado: (2016)