Arsenic-induced Histological Alterations in Various Organs of Mice

Deposition of arsenic in mice through groundwater is well documented but little is known about the histological changes of organs by the metalloid. Present study was designed to evaluate arsenic-induced histological alterations in kidney, liver, thoracic artery and brain of mice which are not well d...

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Autores principales: Noman, Abu Shadat Mohammod, Dilruba, Sayada, Mohanto, Nayan Chandra, Rahman, Lutfur, Khatun, Zohora, Riad, Wahiduzzaman, Al Mamun, Abdullah, Alam, Shahnur, Aktar, Sharmin, Chowdhury, Srikanta, Saud, Zahangir Alam, Rahman, Zillur, Hossain, Khaled, Haque, Azizul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698904/
https://www.ncbi.nlm.nih.gov/pubmed/26740907
http://dx.doi.org/10.4172/2157-7099.1000323
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author Noman, Abu Shadat Mohammod
Dilruba, Sayada
Mohanto, Nayan Chandra
Rahman, Lutfur
Khatun, Zohora
Riad, Wahiduzzaman
Al Mamun, Abdullah
Alam, Shahnur
Aktar, Sharmin
Chowdhury, Srikanta
Saud, Zahangir Alam
Rahman, Zillur
Hossain, Khaled
Haque, Azizul
author_facet Noman, Abu Shadat Mohammod
Dilruba, Sayada
Mohanto, Nayan Chandra
Rahman, Lutfur
Khatun, Zohora
Riad, Wahiduzzaman
Al Mamun, Abdullah
Alam, Shahnur
Aktar, Sharmin
Chowdhury, Srikanta
Saud, Zahangir Alam
Rahman, Zillur
Hossain, Khaled
Haque, Azizul
author_sort Noman, Abu Shadat Mohammod
collection PubMed
description Deposition of arsenic in mice through groundwater is well documented but little is known about the histological changes of organs by the metalloid. Present study was designed to evaluate arsenic-induced histological alterations in kidney, liver, thoracic artery and brain of mice which are not well documented yet. Swiss albino male mice were divided into 2 groups and treated as follows: Group 1: control, 2: arsenic (sodium arsenite at 10 mg/kg b.w. orally for 8 wks). Group 2 showed marked degenerative changes in kidney, liver, thoracic artery, and brain whereas Group 1 did not reveal any abnormalities on histopathology. We therefore concluded that arsenic induces histological alterations in the tested organs.
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spelling pubmed-46989042016-01-04 Arsenic-induced Histological Alterations in Various Organs of Mice Noman, Abu Shadat Mohammod Dilruba, Sayada Mohanto, Nayan Chandra Rahman, Lutfur Khatun, Zohora Riad, Wahiduzzaman Al Mamun, Abdullah Alam, Shahnur Aktar, Sharmin Chowdhury, Srikanta Saud, Zahangir Alam Rahman, Zillur Hossain, Khaled Haque, Azizul J Cytol Histol Article Deposition of arsenic in mice through groundwater is well documented but little is known about the histological changes of organs by the metalloid. Present study was designed to evaluate arsenic-induced histological alterations in kidney, liver, thoracic artery and brain of mice which are not well documented yet. Swiss albino male mice were divided into 2 groups and treated as follows: Group 1: control, 2: arsenic (sodium arsenite at 10 mg/kg b.w. orally for 8 wks). Group 2 showed marked degenerative changes in kidney, liver, thoracic artery, and brain whereas Group 1 did not reveal any abnormalities on histopathology. We therefore concluded that arsenic induces histological alterations in the tested organs. 2015-04-24 2015-05 /pmc/articles/PMC4698904/ /pubmed/26740907 http://dx.doi.org/10.4172/2157-7099.1000323 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Noman, Abu Shadat Mohammod
Dilruba, Sayada
Mohanto, Nayan Chandra
Rahman, Lutfur
Khatun, Zohora
Riad, Wahiduzzaman
Al Mamun, Abdullah
Alam, Shahnur
Aktar, Sharmin
Chowdhury, Srikanta
Saud, Zahangir Alam
Rahman, Zillur
Hossain, Khaled
Haque, Azizul
Arsenic-induced Histological Alterations in Various Organs of Mice
title Arsenic-induced Histological Alterations in Various Organs of Mice
title_full Arsenic-induced Histological Alterations in Various Organs of Mice
title_fullStr Arsenic-induced Histological Alterations in Various Organs of Mice
title_full_unstemmed Arsenic-induced Histological Alterations in Various Organs of Mice
title_short Arsenic-induced Histological Alterations in Various Organs of Mice
title_sort arsenic-induced histological alterations in various organs of mice
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698904/
https://www.ncbi.nlm.nih.gov/pubmed/26740907
http://dx.doi.org/10.4172/2157-7099.1000323
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