ANKS1B Interacts with the Cerebral Cavernous Malformation Protein-1 and Controls Endothelial Permeability but Not Sprouting Angiogenesis

Cerebral cavernous malformations are fragile blood vessel conglomerates in the central nervous system that are caused by mutations in the CCM1/KRIT1, CCM2 or CCM3 genes. The gene products form a protein complex at adherens junctions and loss of either CCM protein disrupts endothelial cell quiescence...

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Detalles Bibliográficos
Autores principales: Herberich, Stefanie E., Klose, Ralph, Moll, Iris, Yang, Wan-Jen, Wüstehube-Lausch, Joycelyn, Fischer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699217/
https://www.ncbi.nlm.nih.gov/pubmed/26698571
http://dx.doi.org/10.1371/journal.pone.0145304

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