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SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients

BACKGROUND: Serine hydroxymethyltransferase 1 (SHMT1) is a key enzyme in the folate metabolic pathway that plays an important role in biosynthesis by providing one carbon unit. SHMT1 C1420T may lead to the abnormal biosynthesis involved in DNA synthesis and methylation, and it may eventually increas...

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Detalles Bibliográficos
Autores principales: Wang, Yi-Wei, Zhang, Shao-Dan, Xue, Wen-Ji, Zhu, Mei-Ling, Zheng, Lei-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699293/
https://www.ncbi.nlm.nih.gov/pubmed/26666829
http://dx.doi.org/10.1186/s40880-015-0065-z