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SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients
BACKGROUND: Serine hydroxymethyltransferase 1 (SHMT1) is a key enzyme in the folate metabolic pathway that plays an important role in biosynthesis by providing one carbon unit. SHMT1 C1420T may lead to the abnormal biosynthesis involved in DNA synthesis and methylation, and it may eventually increas...
Autores principales: | Wang, Yi-Wei, Zhang, Shao-Dan, Xue, Wen-Ji, Zhu, Mei-Ling, Zheng, Lei-Zhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699293/ https://www.ncbi.nlm.nih.gov/pubmed/26666829 http://dx.doi.org/10.1186/s40880-015-0065-z |
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