Transcriptome analysis in calorie-restricted rats implicates epigenetic and post-translational mechanisms in neuroprotection and aging

BACKGROUND: Caloric restriction (CR) can increase longevity in rodents and improve memory function in humans. α-Lipoic acid (LA) has been shown to improve memory function in rats, but not longevity. While studies have looked at survival in rodents after switching from one diet to another, the underl...

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Detalles Bibliográficos
Autores principales: Wood, Shona H., van Dam, Sipko, Craig, Thomas, Tacutu, Robi, O’Toole, Amy, Merry, Brian J., de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699360/
https://www.ncbi.nlm.nih.gov/pubmed/26694192
http://dx.doi.org/10.1186/s13059-015-0847-2

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