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Towards a new era in medicine: therapeutic genome editing
Genome editing is the process of precisely modifying the nucleotide sequence of the genome. It has provided a powerful approach to research questions but, with the development of a new set of tools, it is now possible to achieve frequencies of genome editing that are high enough to be useful therape...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699361/ https://www.ncbi.nlm.nih.gov/pubmed/26694713 http://dx.doi.org/10.1186/s13059-015-0859-y |
| _version_ | 1782408176296001536 |
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| author | Porteus, Matthew H. |
| author_facet | Porteus, Matthew H. |
| author_sort | Porteus, Matthew H. |
| collection | PubMed |
| description | Genome editing is the process of precisely modifying the nucleotide sequence of the genome. It has provided a powerful approach to research questions but, with the development of a new set of tools, it is now possible to achieve frequencies of genome editing that are high enough to be useful therapeutically. Genome editing is being developed to treat not only monogenic diseases but also infectious diseases and diseases that have both a genetic and an environmental component. |
| format | Online Article Text |
| id | pubmed-4699361 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-46993612016-01-05 Towards a new era in medicine: therapeutic genome editing Porteus, Matthew H. Genome Biol Review Genome editing is the process of precisely modifying the nucleotide sequence of the genome. It has provided a powerful approach to research questions but, with the development of a new set of tools, it is now possible to achieve frequencies of genome editing that are high enough to be useful therapeutically. Genome editing is being developed to treat not only monogenic diseases but also infectious diseases and diseases that have both a genetic and an environmental component. BioMed Central 2015-12-22 2015 /pmc/articles/PMC4699361/ /pubmed/26694713 http://dx.doi.org/10.1186/s13059-015-0859-y Text en © Porteus. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Review Porteus, Matthew H. Towards a new era in medicine: therapeutic genome editing |
| title | Towards a new era in medicine: therapeutic genome editing |
| title_full | Towards a new era in medicine: therapeutic genome editing |
| title_fullStr | Towards a new era in medicine: therapeutic genome editing |
| title_full_unstemmed | Towards a new era in medicine: therapeutic genome editing |
| title_short | Towards a new era in medicine: therapeutic genome editing |
| title_sort | towards a new era in medicine: therapeutic genome editing |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699361/ https://www.ncbi.nlm.nih.gov/pubmed/26694713 http://dx.doi.org/10.1186/s13059-015-0859-y |
| work_keys_str_mv | AT porteusmatthewh towardsanewerainmedicinetherapeuticgenomeediting |