Mineotaur: a tool for high-content microscopy screen sharing and visual analytics

High-throughput/high-content microscopy-based screens are powerful tools for functional genomics, yielding intracellular information down to the level of single-cells for thousands of genotypic conditions. However, accessing their data requires specialized knowledge and most often that data is no lo...

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Detalles Bibliográficos
Autores principales: Antal, Bálint, Chessel, Anatole, Carazo Salas, Rafael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Open Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699365/
https://www.ncbi.nlm.nih.gov/pubmed/26679168
http://dx.doi.org/10.1186/s13059-015-0836-5
Descripción
Sumario:High-throughput/high-content microscopy-based screens are powerful tools for functional genomics, yielding intracellular information down to the level of single-cells for thousands of genotypic conditions. However, accessing their data requires specialized knowledge and most often that data is no longer analyzed after initial publication. We describe Mineotaur (http://www.mineotaur.org), a open-source, downloadable web application that allows easy online sharing and interactive visualisation of large screen datasets, facilitating their dissemination and further analysis, and enhancing their impact. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-015-0836-5) contains supplementary material, which is available to authorized users.

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