A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63

BACKGROUND: Open chromatin regions are correlated with active regulatory elements in development and are dysregulated in diseases. The BAF (SWI/SNF) complex is essential for development, and has been demonstrated to remodel reconstituted chromatin in vitro and to control the accessibility of a few i...

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Detalles Bibliográficos
Autores principales: Bao, Xiaomin, Rubin, Adam J., Qu, Kun, Zhang, Jiajing, Giresi, Paul G., Chang, Howard Y., Khavari, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699366/
https://www.ncbi.nlm.nih.gov/pubmed/26683334
http://dx.doi.org/10.1186/s13059-015-0840-9

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