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Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling
BACKGROUND: RNA levels detected at steady state are the consequence of multiple dynamic processes within the cell. In addition to synthesis and decay, transcripts undergo processing. Metabolic tagging with a nucleotide analog is one way of determining the relative contributions of synthesis, decay a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699367/ https://www.ncbi.nlm.nih.gov/pubmed/26679539 http://dx.doi.org/10.1186/s13059-015-0848-1 |