Regulation of YKL-40 expression by corticosteroids: effect on pro-inflammatory macrophages in vitro and its modulation in COPD in vivo

BACKGROUND: Macrophages constitute a heterogeneous cell population with pro- (MΦ1) and anti-inflammatory (MΦ2) cells. The soluble chitinase-like-protein YKL-40 is expressed in macrophages and various other cell types, and has been linked to a variety of inflammatory diseases, including COPD. Dexamet...

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Detalles Bibliográficos
Autores principales: Kunz, L. I. Z., van’t Wout, E. F. A., van Schadewijk, A., Postma, D. S., Kerstjens, H. A. M., Sterk, P. J., Hiemstra, P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699377/
https://www.ncbi.nlm.nih.gov/pubmed/26696093
http://dx.doi.org/10.1186/s12931-015-0314-3

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