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FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway
Microsatellites are short tandem repeat sequences that are highly prone to expansion/contraction due to their propensity to form non-B-form DNA structures, which hinder DNA polymerases and provoke template slippage. Although error correction by mismatch repair plays a key role in preventing microsat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699383/ https://www.ncbi.nlm.nih.gov/pubmed/26637282 http://dx.doi.org/10.1101/gad.272740.115 |