FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway

Microsatellites are short tandem repeat sequences that are highly prone to expansion/contraction due to their propensity to form non-B-form DNA structures, which hinder DNA polymerases and provoke template slippage. Although error correction by mismatch repair plays a key role in preventing microsat...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Kenichiro, Borel, Valerie, Adelman, Carrie A., Schindler, Detlev, Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699383/
https://www.ncbi.nlm.nih.gov/pubmed/26637282
http://dx.doi.org/10.1101/gad.272740.115

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