Floor plate-derived neuropilin-2 functions as a secreted semaphorin sink to facilitate commissural axon midline crossing

Commissural axon guidance depends on a myriad of cues expressed by intermediate targets. Secreted semaphorins signal through neuropilin-2/plexin-A1 receptor complexes on post-crossing commissural axons to mediate floor plate repulsion in the mouse spinal cord. Here, we show that neuropilin-2/plexin-...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez-Enriquez, Berenice, Wu, Zhuhao, Martinez, Edward, Olsen, Olav, Kaprielian, Zaven, Maness, Patricia F., Yoshida, Yutaka, Tessier-Lavigne, Marc, Tran, Tracy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699389/
https://www.ncbi.nlm.nih.gov/pubmed/26680304
http://dx.doi.org/10.1101/gad.268086.115

Ejemplares similares

Ejemplares similares