A pH Sensitive High-Throughput Assay for miRNA Binding of a Peptide-Aminoglycoside (PA) Library

MicroRNAs (miRNA) are small RNAs that have a regulatory role in gene expression. Because of this regulatory role, miRNAs have become a new target for therapeutic compounds. Here, we outline an approach to target specific miRNAs using a high throughput capable assay and a 215 compound peptidic-aminos...

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Detalles Bibliográficos
Autores principales: Watkins, Derrick, Jiang, Liuwei, Nahar, Smita, Maiti, Souvik, Arya, Dev P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699463/
https://www.ncbi.nlm.nih.gov/pubmed/26656788
http://dx.doi.org/10.1371/journal.pone.0144251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699463/
https://www.ncbi.nlm.nih.gov/pubmed/26656788
http://dx.doi.org/10.1371/journal.pone.0144251

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