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Individualized Mutation Detection in Circulating Tumor DNA for Monitoring Colorectal Tumor Burden Using a Cancer-Associated Gene Sequencing Panel

BACKGROUND: Circulating tumor DNA (ctDNA) carries information on tumor burden. However, the mutation spectrum is different among tumors. This study was designed to examine the utility of ctDNA for monitoring tumor burden based on an individual mutation profile. METHODOLOGY: DNA was extracted from a...

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Detalles Bibliográficos
Autores principales:	Sato, Kei A., Hachiya, Tsuyoshi, Iwaya, Takeshi, Kume, Kohei, Matsuo, Teppei, Kawasaki, Keisuke, Abiko, Yukito, Akasaka, Risaburo, Matsumoto, Takayuki, Otsuka, Koki, Nishizuka, Satoshi S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699643/ https://www.ncbi.nlm.nih.gov/pubmed/26727500 http://dx.doi.org/10.1371/journal.pone.0146275

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