Where Have All the Rodents Gone? The Effects of Attrition in Experimental Research on Cancer and Stroke

Given small sample sizes, loss of animals in preclinical experiments can dramatically alter results. However, effects of attrition on distortion of results are unknown. We used a simulation study to analyze the effects of random and biased attrition. As expected, random loss of samples decreased sta...

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Detalles Bibliográficos
Autores principales: Holman, Constance, Piper, Sophie K., Grittner, Ulrike, Diamantaras, Andreas Antonios, Kimmelman, Jonathan, Siegerink, Bob, Dirnagl, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Meta-Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699644/
https://www.ncbi.nlm.nih.gov/pubmed/26726833
http://dx.doi.org/10.1371/journal.pbio.1002331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699644/
https://www.ncbi.nlm.nih.gov/pubmed/26726833
http://dx.doi.org/10.1371/journal.pbio.1002331

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