Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression

Several stressors are known to influence epithelial tight junction (TJ) integrity, but the association between DNA damage and TJ integrity remains unclear. Here we examined the effects of daunorubicin and rebeccamycin, two anti-tumor chemicals that induce DNA damage, on TJ integrity in human intesti...

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Detalles Bibliográficos
Autores principales: Watari, Akihiro, Hasegawa, Maki, Yagi, Kiyohito, Kondoh, Masuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699696/
https://www.ncbi.nlm.nih.gov/pubmed/26727128
http://dx.doi.org/10.1371/journal.pone.0145631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699696/
https://www.ncbi.nlm.nih.gov/pubmed/26727128
http://dx.doi.org/10.1371/journal.pone.0145631

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