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Glucose-Raising Polymorphisms in the Human Clock Gene Cryptochrome 2 (CRY2) Affect Hepatic Lipid Content
Circadian rhythms govern vital functions. Their disruption provokes metabolic imbalance favouring obesity and type-2 diabetes. The aim of the study was to assess the role of clock genes in human prediabetes. To this end, genotype-phenotype associations of 121 common single nucleotide polymorphisms (...
Autores principales: | Machicao, Fausto, Peter, Andreas, Machann, Jürgen, Königsrainer, Ingmar, Böhm, Anja, Lutz, Stefan Zoltan, Heni, Martin, Fritsche, Andreas, Schick, Fritz, Königsrainer, Alfred, Stefan, Norbert, Häring, Hans-Ulrich, Staiger, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699770/ https://www.ncbi.nlm.nih.gov/pubmed/26726810 http://dx.doi.org/10.1371/journal.pone.0145563 |
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