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Effectiveness of Losartan-Loaded Hyaluronic Acid (HA) Micelles for the Reduction of Advanced Hepatic Fibrosis in C3H/HeN Mice Model

Advanced hepatic fibrosis therapy using drug-delivering nanoparticles is a relatively unexplored area. Angiotensin type 1 (AT1) receptor blockers such as losartan can be delivered to hepatic stellate cells (HSC), blocking their activation and thereby reducing fibrosis progression in the liver. In ou...

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Detalles Bibliográficos
Autores principales:	Thomas, Reju George, Moon, Myeong Ju, Kim, Jo Heon, Lee, Jae Hyuk, Jeong, Yong Yeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699854/ https://www.ncbi.nlm.nih.gov/pubmed/26714035 http://dx.doi.org/10.1371/journal.pone.0145512

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