Escherichia coli Heat-Stable Enterotoxin Mediates Na(+)/H(+) Exchanger 4 Inhibition Involving cAMP in T(84) Human Intestinal Epithelial Cells

The enterotoxigenic Escherichia coli strains lead to diarrhoea in humans due to heat-labile and heat-stable (STa) enterotoxins. STa increases Cl(-)release in intestinal cells, including the human colonic carcinoma T(84) cell line, involving increased cGMP and membrane alkalization due to reduced Na(...

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Detalles Bibliográficos
Autores principales: Beltrán, Ana R., Carraro-Lacroix, Luciene R., Bezerra, Camila N. A., Cornejo, Marcelo, Norambuena, Katrina, Toledo, Fernando, Araos, Joaquín, Pardo, Fabián, Leiva, Andrea, Sanhueza, Carlos, Malnic, Gerhard, Sobrevia, Luis, Ramírez, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699896/
https://www.ncbi.nlm.nih.gov/pubmed/26713849
http://dx.doi.org/10.1371/journal.pone.0146042

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