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MAP3K1-targeting therapeutic artificial miRNA suppresses the growth and invasion of breast cancer in vivo and in vitro

Recent investigations have highlighted that therapeutic artificial microRNAs could be promising candidates for cancer therapy through the modulation of tumor promoter or suppressor. MEK kinase 1 (MEKK1) is expressed by mitogen-activated kinase kinase kinase 1 (MAP3K1), an important kinase that links...

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Detalles Bibliográficos
Autores principales: Liu, Chun, Wang, Shengjie, Zhu, Shunxing, Wang, Haifeng, Gu, Jiayi, Gui, Zeping, Jing, Jin, Hou, Xiaofan, Shao, Yixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700027/
https://www.ncbi.nlm.nih.gov/pubmed/26759750
http://dx.doi.org/10.1186/s40064-015-1597-z